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So, I am currently on 100 mg of the combination of both methadone and the patch. I thought my dr wanted me to take both the methadone and patch together, because he said for break thru pain, hell, the pain never has stopped. The other day he said you aren't using the patch and methadone together are. Results 1 - 20 of 81. Methadone Patch - Topics (Showing results 1 - 20 of 81)... methadone patch: my grandaughter has been on methadone drink for five years now and her teeth are rotting away terrib... Methadone With Fentanyl Patch: been with same pm dr. for 4 years has recently retired and now have no dr or meds. I have been on the patches for nine months now, originally given to me for back pain. I have now been referred to my local drug re-abilitation centre to get help with my addiction, they are talking about putting me on Methadone to wean me down slowly.....I know there is stigma attatched to this drug and I,. While patients on both methadone and buprenorphine were found to have lower free testosterone when compared to the reference groups, patients on methadone had lower total testosterone levels versus the buprenorphine group.14 In addition, one study assessed the effects of the buprenorphine patch. Pharm Dev Technol. 1996 Oct;1(3):285-91. Development of a transdermal patch of methadone: in vitro evaluation across hairless mouse and human cadaver skin. Ghosh TK(1), Bagherian A. Author information: (1)Department of Pharmaceutical Sciences, College of Pharmacy and Pharmaceutical Sciences, Howard. J Clin Psychopharmacol. 2009 Jun;29(3):231-8. doi: 10.1097/JCP.0b013e3181a39113. Methadone-nicotine interactions in methadone maintenance treatment patients. Elkader AK(1), Brands B, Selby P, Sproule BA. Author information: (1)Centre for Addiction and Mental Health, Toronto, Ontario, Canada. Smoking is highly. Methadone is a medication used to relieve severe pain. It's also used to prevent withdrawal symptoms in people who are addicted to opiate drugs such as morphine, hydrocodone, oxycodone, and fentanyl. Dolophine and Methadose are two common brand names for methadone. Methadone is a narcotic. The methadone effects are in the central nervous system (CNS) and peripheral, its agonist μ action gives analgesic activity and its NMDA action and the inhibitions over monoamines can has a relevant paper in neuropathic pain treatment. Transdermal patch of methadone was prepared to improve adherence by the patient. Question. My question pertains to combining transdermal fentanyl (Duragesic patch) with either methadone or other short-acting opioids for breakthrough pain, cancerous or noncancerous. For instance, what do you think about using the Duragesic patch with oral transmucosal fentanyl citrate (OTFC [Actiq]). Fentanyl Patch for pain - Methadone Hurts: :woohoo: Wow, so after having taken Methadone up to 40 mgs twice a day for now going on almost a year, has. so i posted a thread a couple days ago, but its gone? :\ im on 75mg liquid methadone daily for 11 years now. well since i've been going to the clinic i like to chase that methadone high. so i get 2-weeks worth of methadone and the first week i double my dose taking 150mg at a time. then the second week i. Dosing Principles. For patients requiring daily opioid therapy for longer than a few days to a few weeks, consider switching from short-acting opioids to long-acting oral therapy. Fentanyl patches are another option, but are expensive and difficult to titrate. Conversion to methadone is appropriate for opioid use greater than. Methadone Withdrawal Patch contains 2 patches good for 6 days or 2 weekends. $29.99 $19.99. Add to cart. SKU: Methadone Withdrawal Patch Categories: Healing & Detox, Rehab. Uses. It is used to ease long-term pain problems. It is used to treat drug addiction and withdrawal. Methadone lowers the feeling of pain and how one reacts to pain. It binds to parts of the brain to lower the need for pain drugs and help with withdrawal signs. I've been on both fentanyl and methadone. To me - there's no med that brings my pain down better than fentanyl. As you know, I use the oral fentanyl. I can't use the patch - as I have very fair skin and it makes my skin break out.... plus, w/ my dysautonomia - my body temp fluctates so much that there were. Development of a Transdermal Patch of. Methadone: In Vitro Evaluation Across. Hairless Mouse and Human Cadaver Skin. Tapash K. Ghosh* and Alireza Bagherian. Department of Pharmaceutical Sciences, College of Pharmacy and Pharmaceutical. Sciences, Howard University, Washington, DC 20059. Received March. Official Title: Transfer From Methadone to Buprenorphine Maintenance Treatment Using Buprenorphine Patches: A Study on Practicability With Patients Maintained With Daily Dosages Between 60mg and 100mg Methadone. Study Start Date : August 2008. Estimated Primary Completion Date : February 2009. Estimated. I just started the patch and I have been on methadone. I have been on as much as 240 mgs and asked to get down to 100mgs and did so about a year ago. Now iam down to 60-80 mgs and have switched to the 50mg patch along with six 15 mg of oxycodone. I'm still in pain. Please let me know what you. I've been on 60 msg of methadone for a year to treat chronic pain. My dr switched me to the fentanyl patch 50 mcgs. Is it possible to have withdrawl symptoms even though I went from one opiate to another? I feel tired achy and my legs feel heavy. I have rls bad and I'm irritable and agitated. I know. He's on methadone right now. HORACE (excitedly): Oh really? Good man. ROBERTO: Yeah, 'cuz I talked him into it 'cuz otherwise I wasn't gonna be his friend no more. HORACE: He got hooked up with the right shit. ROBERTO: Methadone's the shit, man. HORACE: Oh that shit feels good! On a patch on you... Oooohhhh. C. Methadone Methadone [METH-a-done] is a synthetic, orally effective opioid that is approximately equal in potency to morphine but induces less euphoria and has a somewhat longer duration of. The transdermal patch must be used with caution, because death resulting from hypoventilation has been known to occur. Death by fentanyl patch and methadone. more. J Fam Pract. 2011 December;60(12):772-784. Author(s):: Jeffrey L. Susman, MD. Author and Disclosure Information. COMMENTARY PROVIDED BY Jeffrey L. Susman, MD Editor-in-Chief. The cases in this column are selected by the editors of The Journal of Family Practice. Although initially used in cancer patients, methadone is being increasingly used in the end-of-life care setting for patients with nonmalignant pain syndromes. As the only long-acting opioid liquid formulation, methadone provides an attractive alternative to the expensive transdermal fentanyl patch in patients with debilitating. (approximately 20% incidence) and pruritus at the patch-application site. Of the latter one of the previously described studies reported an incidence of 9.3%, vs. 5.1 % after application of placebo patches [62]. A double series of case reports described the problem of allergic contact dermatitis to BUPTDS [87, 88]. Patients. After the patient is started on a fentanyl patch there is a 6-12 h delay in the onset of analgesia, and therefore, patients need to have their pain controlled by the. Advantages to the use of methadone in cancer pain include 48-96% bioavailability, lack of active metabolites, low cost, long half-life resulting in larger intervals. Example: Patient is receiving Oxycodone 5-10mg po q4h = 30-60 mg/day . Using the table below, the equivalent dose of Fentanyl patch would be 25 mcg. top. NOTE: DO NOT use this table to convert to other opiates. Codeine, Fentanyl Patch, Hydromorphone, Meperidine, Methadone, Morphine. saliut je voulais avoir quekques renseignement je part en saison et je suis sous methadone a 50mg par jour comme il m est souvent arrive de rester bloque a cause de la neige et de pas pouvoir descendre choper mon traitement jai pecho 2 boites de patch fentanyl 50microg(je pense que ce sont des. Abstract. Aims. To evaluate the novel use of sweat patches in outpatients attending a methadone maintenance clinic. Design. Assessment of inter-patch reliability and validity of patch results compared to urine tests at the start and end of the patch period. Semi-structured questionnaire on patients' opinion of the patches. Buprenorphine vs. Methadone. February 12, 2013. Buprenorphine and methadone, both being opioids, activate the opioid (mu) receptors on nerve cells. And both drugs have long half-lifes, meaning that they're long-acting medications. The half-life can vary from 24 to 60 hours for buprenorphine, and from 8 to 59 hours for. Transitioning from methadone to Butrans(butrenorphine transdermal patch)? Anyone heard of it?? SnowQueen411. I have been on methadone 80mg and oxycodone 30mg for almost 5 yrs for chronic pain and in the last yr it seems that the medication is only making me feel worse. Everything all the time. The FDA has approved methadone for opiate withdrawal. Other agents that may be useful include morphine, clonidine, dexmedetomidine, phenobarbital, paregoric, chlorpromazine, transdermal clonidine patch,46 and SC fentanyl. Paregoric contains morphine plus papaverine, noscapine, camphor (a CNS stimulant),. Washington DC, DC - Medication-Assisted Treatments like methadone still take a lot of work. But for some people, they're the only way to get off heroin. Some patients may prefer to use transdermal fentanyl because of the convenience of changing a patch every 72 hours rather than taking medication orally. In many of the discussion forums on pain management and palliative medicine methadone is suggested as the answer to a variety of 'challenging' pain syndromes. Fentanyl is by far stronger by weight, and in the hydrochloride form is, according to Wikipedia 50x more potent than heroin. It is active in the microgram range and can even be sold for recreational use on blotters. For pure medical use it is often administered via transdermal patches for long term relief of. In recent years, remarkable advances in sensitive analytical techniques have enabled the analysis of drugs in unconcentional samples, such as sweat. In a study conducted during a methadone maintenance program, PharmChek sweat patches were applied to 20 subjects. The subjects were orally administered methadone. Oxycontin have been strengthened to require failure of two formulary long-acting generic agents, morphine extended release tablets and fentanyl patch. This bullet offers another generic option for treating chronic pain. Review your Patient's Med List Closely for Potential Interactions. Methadone is the leading cause of. In the case of converting morphine to methadone, methadone has a relative potency of 4:1 at lower morphine doses, but becomes much more potent (12:1) in patients converting from very high morphine doses.,; Cross-tolerance: Many references recommend a cross-tolerance reduction between 25-50%. reported as an adverse effect of opioids including methadone and buprenorphine. The current article describes. has been investigated in samples receiving OST, primarily methadone maintained males. Common complaints... testosterone patch therapy in men with opioid-induced androgen deficiency. J. Pain 7: 200-10. The present multi-centre cross-sectional study consecutively recruited 231 patients with opioid dependence from methadone clinics across Ontario, Canada between... Mendelson, J. H., Mendelson, J. E. & Patch, V. D. Plasma testosterone levels in heroin addiction and during methadone maintenance . Trade Name. Generic Name, Sponsor. 1, Avinza, Morphine sulfate extended-release capsules, Pfizer. 2, Butrans, Buprenorphine transdermal system, Purdue Pharma. 3, Dolophine, Methadone hydrochloride tablets, Roxane. 4, Duragesic, Fentanyl transdermal system, Janssen Pharmaceuticals. The pain persisted despite a 400 μg/hr transdermal fentanyl patch, oral methadone 50 mg once a day, and dexamethasone 6 mg every 6 hours for the past week. Fentanyl and methadone were stopped and IV morphine was started and titrated to 100 mg/hr. He still rated his pain as 10 on the NS and had not slept for two. Transdermal fentanyl patches such as Duragesic and Ionsys can create a powerful dependency. They may. Even if you've been changing them every 72 hours, leave the very last patch on until it comes off on its own.. Your doctor might want to switch you to oral morphine, oxycodone, or methadone. Methadone is a synthetic opioid useful in the treatment of opioid dependence. Examples of opioids include: Codeine, Morphine, Heroin, OxyNEO, Oxycodone, Opium, Doda Tea, Percocet, Percodan, Fentanyl Patch, Dilaudid, Demerol, Tylenol #1, 2, 3, 4, etc. Clients on a proper dose of methadone can improve their lives by. DOSE: Pharms - Oxycodone · Pharms - Buprenorphine, (daily). Methadone. oral, Pharms - Fentanyl, (patch). rectal, Morphine · Hydrocodone · Codeine · Pharms - Tramadol. Intranasal Fentanyl. 6. Transdermal Buprenorphine to oral Morphine. 7. Methadone. 8. Abbreviations. 9. References. 9. Acknowledgements and Contributors.. After removal of the buprenorphine patch, a short acting opioid should be prescribed for the initial 24 hours and a long acting opioid commenced after 24hours1. I was a heavy pill abuser, mostly pain pill such as oxycodone, fentanyl patch, ect. I have been going to Meth clinic for around 7 months. I'm on a dose of 120mg. You will get high off of methadone. Maybe not as high the longer you dose, but you will get high. Double D. Thursday, February 19th, 2015. For reasons such as these, staff and patients often prefer the patch over oral clonidine. Patients treated with oral clonidine appear to have more withdrawal symptoms than those treated with transdermal patches. However, controlled studies have not yet confirmed these findings. Methadone. Methadone can. Background. Methadone is a potent opioid with several favorable characteristics, including oral bioavailability of 80%, no active metabolites requiring dose adjustments in renal impairment, low cost, steady analgesic effect, and (possibly) more efficacy when used for neuropathic pain than other opioids. However. Sweat patches (N=350) were collected throughout gestation from 29 opioid-dependent pregnant women participating in an outpatient methadone assisted therapy program. Volunteers provided informed consent to participate in Institutional Review Board-approved protocols. Methadone was eluted from sweat patches with. From the 1960s until the year 2000, methadone was the primary option for people seeking narcotic replacement therapy to minimize withdrawal symptoms. Methadone is an opiate agonist that is prescribed under controlled circumstances to treat the symptoms of opiate withdrawal. In 2000, buprenorphine became the first. The combination of fentanyl (patch form) and methadone is unusual because both are considered long acting meds. Usually, your pm Doc will rx you a long acting med and a short acting med for breakthrough pain. For example, I am using the 100 mcg Fentanyl patch and 30 mg Roxicodone for bt. Liver/Hepatitis Bio Energy Patch. Quick View. Healing & Detox. Liver/Hepatitis Bio Energy Patch. $29.99 $19.99. Sale! Acne Plus Bio Energy Patch. Quick View. Healing & Detox. Acne Plus Bio Energy Patch. $29.99 $19.99. Sale! Codeine Withdrawal Patch. Quick View. Healing & Detox. Codeine Withdrawal Patch. $999.00. When switching to methadone, the starting dose should be 10% to 25% of the equianalgesic dose. Opioid dose should. conversion from fentanyl patches to parenteral. 4Caution: Methadone is appropriate for chronic stable pain in an opioid-tolerant patient, but is usually avoided in opiate-naïve patients. Convert & titrate. Transdermal patch should be used only in opioid tolerant patients. Effects of patch last for 18 - 24 hours after the patch is removed.. Methadone. (Dolophine®). PO. 2.5 mg 1 to 4 times daily. 30 - 240 min. 2 - 4 hr. 4 - 24 hr. Liver. 24 hr. · Used in chronic pain. · Continued dosing can result in accumulation and respiratory. Fentanyl nasal spray5. 0.16. Fentanyl patch6. 7.2. Hydrocodone. 1. Hydromorphone. 4. Levorphanol tartrate. 11. Meperidine hydrochloride. 0.1. Methadone. 3. Morphine. 1. buprenorphine is equivalent to 75 milligrams of oral morphine and that one patch delivers the dispensed micrograms per hour over a 24 hour day. 300-600mg/day. 10 :1. 30-60mg/day. 600-800mg/day. 12 :1. 50-60mg/day. Oxycodone Dose. Oxycodone : Methadone. Estimated Ratios. Methadone Dose. 10-60mg/day. 2 :1. 5-30mg/day. 60-100mg/day. 4 :1. 15-25mg/day. > 100mg/day. 6 :1. Oxycontin Dose. Long-acting. Morphine Dose. Fentanyl Patch Methadone Dose. Methadone: Find the most comprehensive real-world treatment information on Methadone at PatientsLikeMe. 339 patients with fibromyalgia, multiple sclerosis, major depressive disorder, generalized anxiety disorder, diabetes type 2, post-traumatic stress disorder, systemic lupus erythematosus, bipolar disorder, Parkinson's. Some come to this part of Boston to get high. Some come to get clean, ducking into clinics where they receive medicine to free them from heroin's grasp. The people here call it Methadone Mile, and it is the heart of Massachusetts' raging opioid crisis. Methadone. —. 2–4 mg6. Opioid Conversion Table. Adapted on work done by. PHC (funding from the Carrares. Foundation) and FH renal program. 3 Fentanyl transdermal patch is not recommended in opioid-naïve patients.. A 10:1 initial conversion ratio for morphine oral equivalent to methadone is recommended. The data upon which the conversions are based are summarized in the table below. All conversions (except methadone) are made by first calculating the morphine equivalent of the opioid being converted from, and then calculating the specific dose of the opioid being converted to. The formulae for converting methadone. ... dose to an equivalent subcutaneous doseClick here to download; How do you convert methadone from a subcutaneous dose to an equivalent oral doseClick here to download; What is the opioid conversion between tramadol and morphineClick here to download; Opioid Transdermal Patches 2016Click here to download. Forty-eight patients receiving methadone at the Public Service for the Treatment of Drug Dependence of Perugia (Italy) were monitored for 14 days by the analysis of methadone and cocaine present in two sweat patches, each worn for 7 days. The results were compared to those from the analysis of urine samples collected. The methadone maintenance program is effective in reducing injecting behaviour, illicit drug use, criminal activity and the cost to society. High dose sublingual.. Table 4. Comparison of oral morphine and transdermal patch dosage. (The British Pain Society, 2007). Oral morphine. Buprenorphine patch. Fentanyl patch. The use of methadone as an analgesic for severe chronic pain has expanded in recent years. It is effective for some patients,... patch 20 mcg/hour. Butrans. One patch every 72 hours 480 mcg. $495. Fentanyl patches. Fentanyl extended-release 25 mcg/hour Duragesic. One patch every 72 hours 600 mcg. mg. Hydromorphone Oral. mg. Tapentadol Oral. mg. Methadone Oral. mg. Fentanyl SC. mcg. Diamorphine SC. mg. Alfentanil SC. mcg. Hydromorphone SC. mg. Oxycodone SC. mg. Morphine IV. mg. Fentanyl IV. mcg. Fentanyl Patch. mcg/h. Buprenorphine Patch. mcg/h. Morphine Epidural. mg. Morphine Intrathecal. mcg. Methadone prescription is official policy for tackling heroin withdrawal. Its supporters say that despite its disadvantages, it gives the best hope of breaking the chaotic cycle of hardcore heroin use. Methadone has been described as a nicotine patch for heroin addicts - it provides a slow, steady delivery that. Switching from one opioid to another should only be recommended or supervised by a healthcare practitioner with adequate competence and sufficient experience. If uncertain, ask for advice from a more experienced practitioner. Opioid rotation or switching may be considered if a patient obtains pain relief with one opioid. Data regarding the buprenorphine 3–4-day patch and the fentanyl 3-day patch were systematically reviewed. Due to lack of studies directly comparing buprenorphine and fentanyl, data comparing these with other step-3 opioids (e.g., oral morphine, oxycodone, and methadone) were also examined. I have been taking 50mg of Methadone (tabs) for Pain Relief for the last 2 years with great results--after trying the gammet (Oxy, Diladud, etc) I found Methadone to be the ticket to opiate pain relief. Lately, I wanted to try a pain patch to combine with Methadone to try and get more extended relief, my doc. tapering of opioids, prescribing of naloxone, or other measures to reduce risk of overdose. 50 MME/day: • 50 mg of hydrocodone (10 tablets of hydrocodone/ acetaminophen 5/300). • 33 mg of oxycodone (~2 tablets of oxycodone sustained-release 15 mg). • 12 mg of methadone ( methadone 5 mg). 90 MME/day:. In essence, after calculating a conversion to morphine (or equivalent), one cannot simply stop the methadone and substitute with the equivalent dose because both drugs will remain in.... I am in withdrawal because surgeon but on 75 fentanyl patch plus 5 mg of oxycodone short acting, take 3 every 6 hrs. OARRS Opioid Conversion Table. MEM = Morphine Equivalent Mul!plier. MEM. Hydrocodone. 1. Oxycodone. 1.5. Codeine. 0.15. Morphine. 1. Buprenorphine 10. Buprenorphine patch 12.6. MEM. Tramadol. 0.1. Fentanyl. 7.2. Methadone. 3. Hydromorphone 4. Oxymorphone. 3. Tapentadol. 0.4. Methadone, 10-40 mg PO. Hydromorphone, parenteral, 9-12 mg IM, SC, IV. Hydromorphone, oral, 45-60 mg PO. Oxycodone, 120 mg PO. Fentanyl, 50-100 mcg/h patch (change q72h). Codeine, 1200 mg PO. Hydrocodone, No consensus on equivalent dose. All equivalencies are approximations, not starting doses. There is. Mezolar Matrix 37.5 microgram/hour transdermal patch - by Sandoz Limited.. oral. 7.5. parenteral. 15b. methadone. oral. 1.5. parenteral. 3b. oxycodone. oral. 1.5. parenteral. 3. oxymorphone. rectal. 3. parenteral. 30b. pethidine. oral. -. parenteral. 0.4b. tapentadol. oral. 0.4. parenteral. -. tramadol. oral. 0.25. parenteral. 0.3. Rationale and design of a randomized controlled trial of varenicline directly observed therapy delivered in methadone clinics. Shadi NahviEmail author,; Kate S Segal,; Alain H Litwin and; Julia H Arnsten. Addiction Science & Clinical Practice20149:9. https://doi.org/10.1186/1940-0640-9-9. © Nahvi et al.; licensee BioMed. While fentanyl patches can be very effective for relieving chronic pain, sometimes keeping them from falling off presents quite a challenge. Since how to keep these patches on is a question that comes up here repeatedly, I've done some research and compiled what seems to be the best recommendations. The bone masses have spurs also. I have used Oxycontin, methadone, fentanyl and morphine. I had a bad reaction to the morphine. I am currently taking methadone and starting to have the normal tolerance problem. I like the fentanyl patch a lot, but that doesn't last long until tolerance builds up. I thought. 9 min - Uploaded by 16x9onglobalMy doctor was prescribing me 225 micro grams ever 48 hours (not 72) on top of 125 mg of. LSD Pure Crystal/Powder Methadone Powder Methadone Pills Stadoll (nasal spray) Dextropropoxyphene 2-FA 2-FMA Psilocin Subutex 2mg. Subutex 8mg 6-APB Trans-4-methylaminorex. TMA-6. Subutex Methylphenidate Phencyclidine (PCP) - Powder Phencyclidine (PCP) - Tablets 5-APB 2-AI Butylone hydromorphone and tramadol; methadone (long acting due to its prolonged elimination half-life); and transdermal fentanyl and.. Methadone. Physeptone tabs 10mg. Hydromorphone. Jurnista 4, 8, 16, 32, 64mg. Dilaudid tabs 2,4,8 mg and liquid 1 mg/ml. Fentanyl. Durogesic patch 12, 25,50,75,100mcg/hr. Buprenorphine. ... Fentanyl dependence; Heroin dependence; Long term methadone therapy for drug abuse; Long-term current use of methadone for drug abuse; Opioid dependence; Opioid dependence (moderate use disorder); Opioid dependence (severe use disorder); Opioid dependence, continuous; Opioid dependence, episodic. was 16-53 with an average age of 37. Southwestern Virginia is currently a "hot spot" for misuse and abuse of oxycodone and methadone. The rapid rise in the number of fentanyl cases over the past three years, the increasing availability of fentanyl patches, and the large number of case histories indicating misuse or abuse. Abusers will squeeze the liquid or gel out of these patches and smoke, ingest or place the solution under the tongue. There is also. Methadone, Suboxone and even pharmaceutical heroin (diacetylmorphine) are used in various locations to prevent withdrawal, but help a person discontinue illicit abuse of different opiates. Methadone is commonly given to people trying to kick a heroin addiction. But the long-lasting opioid is also an inexpensive, effective pain-killer. With rising costs of prescription narcotics like OxyContin, doctors are increasingly prescribing methadone to treat pain, especially to patients on Medicaid or less. After making the diagnosis of serotonin syndrome, haloperidol, fentanyl patch, oxycodone/acetaminophen, citalopram, and mirtazapine were discontinued. RB had. In case one, decreasing the dose of methadone, and in case two, replacement of serotonergic opioids (oxycodone and fentanyl) by a nonserotonergic opioid. My wife is 48 and has MS she is in constant pain cant hardly get her to get out of the chair , She is taking fentanyl patch and hydrcodone for pain , but it is no longer helping, her pain specialists wants her to try Methadone . I have some concerns and was wondering if anyone was using or has used. 7 day patches in much lower doses (Butrans) are also available (5, 10 and. 20mcg/hour). Buprnorphine plasma concentrations and pain relief is not affected by haemodialysis. 8. Methadone. Discuss with consultant if considering using methadone. Useful drug in renal failure especially if pain is neuropathic as it is. Oxycodone. MR BD (o). Oxycodone. 4hrly (sc). Total 24h. (sc). Oxycodone. Diamorphine. 4hrly (sc). Total 24 h. (sc). Diamorphine. Fentanyl patch. 72hrly. 5mg. 20mg1. 30mg. 2.5mg. 10mg. 15mg. 1.25-2.5mg. Methadone conversion more complex and not dealt with here. 1 Rounded up to take into account specific tablet. The current J of Clinical Oncology has a nice little article about one group's experience converting TTS fentanyl to methadone or vice versa. They chose an ratio of fentanyl to methadone of 1:20 [eg 175mcg/h of TTS fentanyl = 4.2mg fentanyl/24hrs = 84mg methadone/24h] &, to make a long story short, had.